Searchable abstracts of presentations at key conferences in endocrinology

ea0049gp78 | Diabetes & complications 1 | ECE2017

Contribution of genetic predisposition and lifestyle to gestational diabetes risk

Popova Polina , Tkachuk Alexandra , Bolotko Yana , Gerasimov Andrey , Klyushina Alexandra , Kostareva Anna , Grineva Elena

Aim: The aim of our study was to assess the contribution of genetic variation in some previously reported gestational diabetes mellitus (GDM) susceptibility loci and lifestyle parameters to GDM risk.Methods: We performed a case-control study of 278 GDM cases and 179 controls who had filled up special questionnaires concerning their lifestyle habits during the oral glucose tolerance test (OGTT) on the 24–32 week of gestation. The questionnaire consis...

ea0081ep917 | Reproductive and Developmental Endocrinology | ECE2022

Machine learning-based model for gestational diabetes mellitus prediction in the first trimester of pregnancy

Popova Polina , Tkachuk Aleksandra , Klyushina Alexandra , Vasilyeva Lyudmila , Vasukova Elena , Anopova Anna , Pustozerov Evgenii , Teplova Yana , Grineva Elena

Background and aim: Gestational Diabetes Mellitus (GDM) is often diagnosed at 24-28 weeks of pregnancy when the fetal phenotype is already altered. We aimed to develop a machine learning model based on clinical variables, lifestyle features and genetic markers for GDM prediction in the first trimester of pregnancy based on the 2013 World Health Organization (WHO) criteria.Methods: Using multivariable logistic regression analysis, different models to pred...